Prepare for the evolution of biosafety patterns

2022-08-23
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Prepare for the evolution of biosafety patterns

biosafety belongs to non-traditional safety. At present, there are mainly 9 kinds of organisms, such as global major infectious diseases, biological weapons threat, bioterrorism, biological invasion and loss of biodiversity, microbial drug resistance, laboratory biosafety, misuse of biotechnology, loss and plagiarism of genetic resources, genetically modified organisms, etc. Jinan new era Gold Testing Instrument Co., Ltd. has produced experimental machines for several 10 years, which has a safety type. Looking ahead, with the global population growth, climate change, technological change and economic transformation, external and internal risks and threats may be comprehensively fermented. At the same time, emerging biosafety patterns are emerging and will bring greater security threats. Therefore, it is an urgent strategic choice to strengthen the research and judgment of future biosafety patterns, improve the national biosafety governance capacity, and comprehensively practice the overall national security concept

Evolution Law of biosafety forms

from the origin and evolution law of biological hazards, natural and ecological factors are the background of various biosafety forms, and scientific and technological factors are accelerators. Biosafety patterns such as naturally occurring major infectious disease outbreaks, biological invasion and transgenic and microbial drug resistance caused by biological interaction originate from the existence of microorganisms and alien species in nature. Because human production and life are affected and human survival is challenged, they are classified as pathogenic microorganisms, harmful animals, harmful alien species and drug-resistant microorganisms. Other types of biosafety cannot jump out of these biological groups and life phenomena that exist in nature. Moreover, the loss of genetic resources and plagiarism do not necessarily lead to direct biological health hazards, but scientific and technological progress not only endows human beings with the ability to manipulate natural biological factors, which can lead to the continuous emergence of new materials, and puts forward higher requirements for the design of fixtures, but also induces new forms of biosafety, such as biological weapons, bioterrorism, antibiotics, laboratory biosafety, misuse of biotechnology, transgenic, etc. There are significant differences in the occurrence frequency, intensity, intensity and extent of spread of these biosafety forms, but there is no essential difference from the microscopic mechanism

from the perspective of biosafety hazard impact, public policy and management, different biosafety forms involve diversified subjects, and policies should be implemented according to needs. At present, the global epidemic of major infectious diseases, microbial drug resistance and species extinction have become common challenges faced by all mankind. The United Nations Environment Programme estimated in 2017 that about 700000 people worldwide die of drug-resistant bacterial infections every year. The United Nations 2019 global biodiversity report warns that 1million of the world's nearly 8million species are facing extinction. Both traditional biological weapons and bioterrorism are malicious uses of pathogenic microorganisms, but there are differences between them: the use of biological weapons is a national act, which has been included in the control scope of the International Convention on the prohibition of biological weapons, while bioterrorism is an act condemned by all mankind. Such biosafety patterns urgently need to strengthen global governance. For the loss and plagiarism of genetic resources, we should emphasize benefit sharing and information transparency. With the development of biotechnology, laboratory biosafety should emphasize the principles of industrial risk prevention, risk system and occupational safety; For the misuse of biotechnology, we need to highlight the scientific spirit and ethics, and draw a clear legal bottom line. Due to the lack of systematic and strict safety scientific research foundation, and the development in the highly competitive business environment, commercial transgenic involves many market players and their interest propositions. The systematization and refinement of policies is the trend

research and judgment of future biosafety patterns

new nature. Biosafety is intertwined with cybersecurity, economic security and scientific and technological security, forming forms such as cybersecurity and Bioeconomic security, which have cross attributes, further mutating the essence of safety and further improving the safety status. For example, computer viruses such as "earthquake" invade the computer equipment in the biological laboratory, which will cause disaster scenes and promote the formation of network biosafety. The biological information resource integration of science and technology system, health department, agricultural department, customs department and commercial system, and the monitoring and supervision information platform of technology and items are likely to become emerging risk points in the future. Bioeconomy security is a new concept. Its core content includes the security of biotechnology talents, intellectual property protection, bioeconomy value chain protection and foreign capital review mechanism, network security and information sharing

development engineering plastics account for about 10%, and developing countries face more thorny challenges. Specifically, the key common technologies, cutting-edge leading technologies, modern engineering technologies and other fields of biotechnology and industry are controlled by people to varying degrees. The engineering, refinement and precision of biological manufacturing equipment are relatively backward, and there are systemic risks in Biotechnology R & D systems and industrial systems. At the same time, biotechnology is a typical dual-use technology. The more it develops, the more dual-use it becomes. There is a problem of social operation safety of science and technology, which puts forward higher requirements for public scientific literacy and national governance strategies

"new wine in old bottles". In the past, the form of biosafety has been upgraded, and its potential harm has become increasingly prominent. For example, technology driven biological species security, new generation biological weapons, etc. Population genetic manipulation can reduce the number of target species or spread some biological effects by accelerating gene migration across species and breaking the natural genetic isolation and reproductive isolation between biological species. Before realizing all the control processes from data collection, PID operation, Ethernet communication to output control in a short time, the "gene drive" has been realized in mammals. The gene drive system has increased the genetic probability of the mutant gene from 50% to 99.5%, which can be used to eliminate species. An internationally renowned think tank research report pointed out that the use of artificial intelligence technology, 3D printing technology, robot technology, to improve the traditional biological weapons, so that they have stronger toxicity or drug resistance, more flexible release methods, better adapt to the changes of climate, terrain and other external environment, and have the characteristics of longer incubation period, more difficult to trace and detect. Synthetic biological technology and neural manipulation electromagnetic technology have broad prospects for the application of offensive biological weapons, which are beyond the control of the biological weapons convention

The fact that emerging biosafety patterns are emerging shows that the development of human society and scientific and technological progress are gradually promoting the highlighting of the inherent risks of biotechnology, and further amplifying the double-edged sword effect of science and technology. Moreover, it can be boldly predicted that there will be diverse forms of biosafety in the future, and its status will even be further improved

strategies for deepening national biosafety governance

insight into the situation and trends, and carry out strategic assessment of national biosafety. "Looking at Jinsong in the twilight, flying across the clouds is still calm", it is very important to maintain strategic concentration. As a key link of national strategic decision-making, national biosafety environmental net assessment is very important and urgent. Because it involves many actors and subjective and objective elements, there are many difficulties in doing this work well. In order to effectively clarify the current and future macro picture of biosafety and national security, we need to change our thinking, form a set of more scientific processes and technical methods, restore the true nature of different forms of biosafety risks, and avoid the two extreme risks of insufficient awareness and excessive anxiety. At the same time, we should identify biological risk factors at the source or at the key links of the prevention and control chain, gradually compress various biological risk spaces, and avoid unnecessary consumption of national strategic capabilities

introduce appropriate governance tools and coordinate the positive factors with people, technology and system as the core. Biosafety is human security, and maintaining biosafety also needs to be human centered. First, create a dialogue platform and cooperation space, improve the effective interaction between biotechnology academia, biotechnology industry, finance, social institutions and groups, improve the national awareness of biosafety, and strengthen biosafety education. Formulate the national biosafety strategy and biosafety law, clarify the specific implementation plan or rules, and establish a mechanism for reporting to the National People's Congress. Second, adhere to both safety and development, improve the system and scientific and technological supervision of key core technologies, adhere to the development of biotechnology to ensure biosafety, accelerate the formation of national biosafety basic capabilities, and firmly grasp the strategic initiative of biosafety. Aiming at the problem of endogenous biosafety risks, we should implement the principles of risk prevention, sustainable development and dynamic supervision, establish risk assessment systems, directory and list management systems and other systems, and delimit the behavior boundary. We should comprehensively consider many strategies, means and tools of national biosafety strategic objectives and implementation, biosafety theory and institutional innovation, biosafety think tanks, and biosafety capacity assessment, and work from multiple ends to form integrated advantages, effectively reflecting institutional and governance advantages

coordinate domestic and international biosafety with a community with a shared future for mankind. Actively review and look forward to the basic propositions, core issues, basic elements and the complex theoretical system of national biosafety, so as to promote the innovation of biosafety theory and the innovation of biosafety practice measures and value propositions. Facing the future, we should actively respond to the great needs of international biosafety, take the United Nations and its subordinate international organizations, the Convention on the prohibition of biological weapons, the Convention on biological diversity, the international health regulations and other international coordinated governance platforms and mechanisms as the core, and comprehensively apply the coordinated governance model of individuals, groups, countries, international and global levels

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